Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats
Published in Molecular Psychiatry, this new study gives some observational data to support people’s anecdotal reports on the benefits of microdosing.
Researchers gave a microdose-like regimen to rats, using repeated low doses of psilocybin. The rodents tolerated the repeated low doses of psilocybin well and did not manifest signs of anxiety, altered locomotor activity, or anhedonia (loss of ability to feel pleasure, common symptom of depressive disorders).
According to the study:
“…the repeated low doses of psilocybin imparted resilience against the stress of multiple subcutaneous injections, and reduced the frequency of self-grooming, a proxy for human compulsive actions.”
Compulsive self-grooming — does sound like something I might do when stressed. More microdoses please.
Read more here.
